Warning: include_once(_inc/initialize.php): failed to open stream: No such file or directory in , on line 2

Warning: include_once(): Failed opening '_inc/initialize.php' for inclusion (include_path='.;C:\php\pear') in , on line 2

Fatal error: Uncaught Error: Call to a member function execute() on null in ,:41
Stack trace:
#0 {main}
  thrown in , on line 41